Diazomethane without distillation

A quick note on something else in the magazine this week: A story by Beth Halford on a new way to make diazomethane in situ, without distillation. As Beth notes, diazomethane is both explosive and toxic, and the common alternative trimethylsilyldiazomethane is less explosive but probably NOT less toxictwo chemists died in 2008 from trimethylsilyldiazomethane exposure. Anything that makes the reagents safer to handle seems like a definite plus. Go read.

Author: Jyllian Kemsley

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