http://cenblog.org/the-haystack/2012/02/drug_design/ C&EN's pharmaceutical and biotech blog Tue, 23 Apr 2013 04:42:25 +0000 hourly 1 http://wordpress.org/?v=3.5.1 http://cenblog.org/the-haystack/2012/02/drug_design/comment-page-1/#comment-107213 H2L Fri, 24 Feb 2012 03:52:30 +0000 http://cenblog.org/the-haystack/?p=2193#comment-107213 The first graphic seems perfectly clear. There is a big red “X” between the drug and the decoy, indicating you do not want to go down that path.

]]> http://cenblog.org/the-haystack/2012/02/drug_design/comment-page-1/#comment-106825 gippgig Wed, 22 Feb 2012 09:06:16 +0000 http://cenblog.org/the-haystack/?p=2193#comment-106825 This doesn’t make it clear that the decoy is what you’re trying NOT to bind to; the object is to selectively bind to the target (producing the therapeutic effect) without binding to any decoys (producing presumably undesirable side effects).

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