Using Gene Expression Patterns to Repurpose Drugs
Late last month, researchers from many different fields gathered at the Computer History Museum in Mountain View, California, to discuss the benefits of open science and data sharing. One of the best talks from that event, the Open Science Summit, was delivered by Joel Dudley, the co-founder of NuMedii, a firm that aims to find new indications for medications.
Dudley has repeatedly found new uses for old drugs by picking through public data sets about the gene expression profiles of different diseases. He then looks for medications that are known to reverse those profiles.
Much of the data that Dudley uses comes from the Gene Expression Omnibus, which he regards as a gold mine.
A full list of videos from the Open Science Summit is also available.