arrow2 Comments
  1. John Beutler
    Jul 13 - 11:38 am

    That’s no ketone, it’s an ester!

  2. See Arr Oh
    Jul 13 - 2:20 pm

    @John Beutler: Yup, you’re right, it sure is. I got caught up trying to describe what constituted a “traditional” Michael acceptor, and forgot to glance back at the structure!

    This system would be less electrophilic than a normal enone, but would still potentially bind to nucleophilic biomolecules.

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