What Are Your Favorite Non-U.S. Drug Discovery Stories?
Jun18

What Are Your Favorite Non-U.S. Drug Discovery Stories?

Over at my other gig at the Pharma & Healthcare section of Forbes.com, I’ve been covering a few stories of new drugs and improvements on old drugs. Although I’m focusing on natural products like vancomycin and semi-synthetics like lurbinectedin, I’ve been thinking a bit about the stories behind the discoveries of all drugs. Part of my thinking has been driven by my current reading of Happy Accidents: Serendipity...

Read More
Mourning Open Notebook Science Pioneer, Dr. Jean-Claude Bradley
May14

Mourning Open Notebook Science Pioneer, Dr. Jean-Claude Bradley

I’ve have more later but I just learned some very sad news from Antony Williams: Drexel University chemist, Jean-Claude Bradley, passed away yesterday. Antony has some personal reflections of his dear friend at his site but here is the official letter from Drexel: Dear Members of the Drexel University Community, It is with deep sadness that I inform you of the passing of Jean-Claude Bradley, PhD, associate professor in the...

Read More
New University of Florida Chemistry Building Is A “Go!” – Again
May06

New University of Florida Chemistry Building Is A “Go!” – Again

Well, it’s that time of the academic year to dust off my University of Florida doctoral regalia for this weekend’s commencement activities at my North Carolina institutions. It’s always a delight to be reminded of my graduate school days in UF’s Department of Pharmacology and Therapeutics. So, I was pleased to receive an email from UF that, last Thursday, the Florida Legislature really, really appropriated $20...

Read More
Google Features Percy Julian, Legendary African-American Chemist
Apr11

Google Features Percy Julian, Legendary African-American Chemist

What a fantastic surprise this morning on the 115th anniversary of Percy Julian’s birth:     I’m beside myself with joy to see this pioneering chemist be recognized by the most prominent search engine in the world. I don’t know where to begin about Julian but I’m sure that many of you have seen The Forgotten Genius, the PBS-produced NOVA life story of the chemist. Julian suffered many indignities in...

Read More
The Case Of The Malodorous Metabolite
Apr06

The Case Of The Malodorous Metabolite

Over where I also write at Forbes.com, Matthew Herper, Senior Editor for Pharma and Healthcare, reported on GlaxoSmithKline’s NEJM clinical trial of darapladib in coronary artery disease. The drug had been developed as a small molecule, orally-formulated, subnanomolar inhibitor of lipoprotein-associated phospholipase A2. Lp-PLA2 is associated with apolipoprotein B-containing lipoproteins, such as LDL and non-HDL particles, and...

Read More